For pharmaceutical companies and researchers

This map is free to reuse under CC BY 4.0, including commercially, to lower the cost and broaden the search for non-opioid analgesics. Every read and gate regenerates deterministically offline from public promoter sequence. All clinical magnitudes are open and remain the reusing party's own scientific, ethical, and regulatory responsibility. A Zenodo DOI is pending.

Reuse is governed by CC BY 4.0 (commercial use permitted). The reproducibility path is closed inside the package: clone the repository and run repro/run_all.py for 11/11 gate checks at drift 0. The map supplies graded target reads and a direction of intervention; potency, selectivity in vivo, efficacy, safety, formulation, and dose are [O] and supplied by the reuser.

Free to reuse

This map is free to reuse — including commercially — under CC BY 4.0, to lower the cost and broaden the search for non-opioid analgesics.

• License. CC BY 4.0. Reuse, adapt, and build on the reads and the lever map with attribution; commercial use is permitted.
• Reproduce. Every read and gate regenerates deterministically (offline, drift 0) from public promoter sequence: clone https://github.com/rego093-sketch/jamming-physics and run repro/run_all.py.
• What you get. 27 graded target reads, a three-lever direction of intervention, a burden-weighted prioritisation, an L3-honesty gate, and a precision local-anaesthesia map — each target a separate page.
• What you must supply. All clinical magnitudes — potency, selectivity in vivo, efficacy, safety, formulation, dose — are [O] open here and remain your own scientific, ethical, and regulatory responsibility.
• Contact / cite. Young Jae Lee, ORCID 0009-0002-7535-8245. A Zenodo DOI is pending and will be inserted on publication.