Diseases — L

47 diseases in this group. Each links to a full page: the emergence switch, the forced corrective direction, mapped agents, and the firewall. Direction only — no dose.

• L-2-hydroxyglutaric aciduriaHOLD · ↑ UP · restore by clearL2HGDH
• Leukocyte adhesion deficiency type 1HOLD · ↓ DOWN · restore by supplyITGB2
• Lamellar ichthyosisMATCH · ↑ UP · restore by clearALOX12B
• Lamellar ichthyosisMATCH · ↑ UP · restore by clearNIPAL4
• Lamellar ichthyosisMATCH · ↑ UP · restore by clearTGM1
• Laron syndromeMATCH · ↓ DOWN · restore by supplyGHR
• Larsen syndromeHOLD · ↑ UP · restore by clearFLNB
• Leber congenital amaurosis 10HOLD · ↓ DOWN · restore by supplyCEP290
• LCANOVEL · ↓ DOWN · restore by supplyLRAT
• LCA / RPHOLD · ↓ DOWN · restore by supplyRDH12
• LCAHOLD · ↓ DOWN · restore by supplySPATA7
• LCHAD deficiencyMATCH · ↓ DOWN · restore by supplyHADHA
• Leber congenital amaurosis type 2MATCH · ↓ DOWN · restore by supplyRPE65
• Leber congenital amaurosisHOLD · ↓ DOWN · restore by supplyAIPL1
• Leber congenital amaurosisHOLD · ↓ DOWN · restore by supplyGUCY2D
• Leber congenital amaurosisHOLD · ↓ DOWN · restore by supplyRPGRIP1
• Legius syndromeNOVEL · ↑ UP · restore by clearSPRED1
• Leigh syndromeHOLD · ↓ DOWN · restore by supplyNDUFS4
• Leigh syndromeHOLD · ↓ DOWN · restore by supplyNDUFV1
• Leigh syndromeHOLD · ↓ DOWN · restore by supplySURF1
• Leigh syndromeHOLD · ↓ DOWN · restore by supplyNDUFS1
• Leigh syndromeHOLD · ↓ DOWN · restore by supplySDHA
• Leptin receptor deficiencyMATCH · ↓ DOWN · restore by supplyLEPR
• Lesch-Nyhan syndrome -- urate axisMATCH · ↑ UP · restore by clearHPRT1
• LGMD D1HOLD · ↓ DOWN · restore by supplyDNAJB6
• LGMD R12HOLD · ↓ DOWN · restore by supplyANO5
• LGMD R1HOLD · ↓ DOWN · restore by supplyCAPN3
• LGMD R2 dysferlinopathy OMIM 253601HOLD · ↓ DOWN · restore by supplyDYSF
• LGMD R3HOLD · ↓ DOWN · restore by supplySGCA
• LGMD R4HOLD · ↓ DOWN · restore by supplySGCB
• LGMD R5HOLD · ↓ DOWN · restore by supplySGCG
• LGMD R6HOLD · ↓ DOWN · restore by supplySGCD
• LGMD R9HOLD · ↓ DOWN · restore by supplyFKRP
• Lipoic acid synthetase deficiencyHOLD · ↓ DOWN · restore by supplyLIAS
• Liddle syndromeMATCH · ↑ UP · restore by clearSCNN1G
• LissencephalyHOLD · ↓ DOWN · restore by supplyDCX
• Lissencephaly 1HOLD · ↓ DOWN · restore by supplyPAFAH1B1
• Loeys-Dietz 1MATCH · ↑ UP · restore by clearTGFBR1
• Loeys-Dietz 3MATCH · ↑ UP · restore by clearSMAD3
• Loeys-Dietz syndromeMATCH · ↑ UP · restore by clearTGFBR2
• Long QT syndrome type 3MATCH · ↑ UP · restore by clearSCN5A
• Lowe oculocerebrorenal syndromeHOLD · ↓ DOWN · restore by supplyOCRL
• Long QT syndrome 1MATCH · ↑ UP · restore by clearKCNQ1
• Long QT syndrome 2MATCH · ↑ UP · restore by clearKCNH2
• Left-ventricular noncompaction cardiomyopathyHOLD · ↓ DOWN · restore by supplyMYH7
• Lysinuric protein intoleranceMATCH · ↓ DOWN · restore by supplySLC7A7
• Lysosomal acid lipase deficiencyMATCH · ↓ DOWN · restore by supplyLIPA