The skin — the body's boundary — emerges from one bistable substrate and four measured master-gene γ values. No constant is fitted to a skin phenotype: each is a measured input or substrate-derived, and every claim is graded and reproducible to an identical hash.
This research preview puts the integumentary system under a wide stress sweep: the epidermal water barrier, wound healing as an unjamming transition, melanin as an ultraviolet feedback screen, epidermal turnover as a dwell-cascade, sweating as a regulated interface flux, and ultraviolet carcinogenesis. Start anywhere:
- 01. EmergenceIntegumentary emergence: the body boundary from measured master-gene γ
- 02. Barrier / TEWLEpidermal barrier and transepidermal water loss: threshold and collapse
- 03. Wound healingWound healing as jamming, unjamming and re-jamming
- 04. Melanin / UVMelanin photoprotection as ultraviolet negative feedback
- 05. TurnoverEpidermal turnover as a substrate dwell-cascade
- 06. ThermoregulationThermoregulation: the sweat gland as a regulated interface flux
- 07. UV carcinogenesisUltraviolet carcinogenesis: the squamous/melanoma dose-response dichotomy
- 08. MethodsMethods, grades and reproducibility
- 09. PathologyIntegumentary pathology: thirteen diseases as perturbations of the verified mechanisms
- 10. Hair cycleThe hair-follicle cycle: an emergent oscillator and four alopecias
- 11. Sebaceous ductThe sebaceous duct: follicular occlusion as a hysteretic jam, with acne and hidradenitis suppurativa
- 12. Cell adhesionCell adhesion as a hysteretic binding jam: pemphigus vulgaris and bullous pemphigoid
- 13. Neurovascular reactivityNeurovascular reactivity as a hysteretic vasomotor jam: rosacea and Raynaud phenomenon
- 14. Cross-package seamsCross-package seams: what the integumentary package imports, exposes, and hands off
Author Young Jae Lee (ORCID 0009-0002-7535-8245) · VP Theory -- Jammed-Granular-Vacuum Emergence · version 1.0.0 · build 2026-06-19 · reproducible engine bundled under repro/.