§12 · the application plane
The applications live on the (gamma, A4) plane, bounded by a contact curve
Vaccines and therapy live on the (γ, A4) plane. Prime-boost dose is coordinate-dependent (it reaches memory at a contact coordinate, fails at a non-contact one of the same γ); the two levers partition the plane; and the 3D contact-boundary curve δ*(γ) rises with γ — a deeper switch needs more contact-assist to stay drive-reachable. [V].
At a fixed immune γ = 1.4892, a prime of 0.5946 with contact-assist 0.2098 reaches memory at a contact coordinate yet fails at a non-contact one. The drive-reachable boundary δ*(γ) rises monotonically from 0.1705 to 0.3428.
Dose is a coordinate, not a scalar
At one immune γ = 1.4892, the same prime reaches the protected basin at a contact-competent coordinate (assist 0.2098) but fails at a non-contact coordinate of identical γ. The effective dose depends on where on the A4 plane the target sits.
The two levers partition the plane
With a tolerable drive of 2.30 spinodal-units, the integration panel of 25 loci splits cleanly into a drive-reachable (Lever B) region and an edit-only (Lever A) region — the therapeutic map is a partition of (γ, contact), and the prediction matches the integrated run.
The contact boundary bends with the barrier
The key application result is a curve, not a point: the minimum contact-assist δ*(γ) needed to keep a switch drive-reachable rises with γ. A deeper switch (harder to flip) needs more A4 contact-help to remain reachable by a tolerable drive — the geometric law tying the two channels to the applications.
| γ | δ* (min contact-assist) |
|---|---|
| 1.300 | 0.1705 |
| 1.323 | 0.1855 |
| 1.345 | 0.2007 |
| 1.368 | 0.2160 |
| 1.391 | 0.2314 |
| 1.414 | 0.2469 |
| 1.436 | 0.2626 |
| 1.459 | 0.2784 |
| 1.482 | 0.2943 |
| 1.505 | 0.3103 |
| 1.527 | 0.3265 |
| 1.550 | 0.3428 |