Lever 2 — increase the outward K⁺ current

Lever 2 — increase the outward K⁺ current. Lever 2 increases the outward K⁺ (M-current) brake, hyperpolarising the neuron and restoring its OFF basin. The K_V7 family is the template (a clinically realised opener arm). The promoter reads place each gene on the threshold scale; direction is cited Layer-2 biology, reads are [V], clinical magnitudes are [O].

This lever groups the targets whose promoter reads place them in the lever 2 — increase the outward k⁺ current. Each target keeps its own page with its read, grades, citation, and firewall; the lever direction is cited Layer-2 biology, the reads are [V], and all clinical magnitudes are [O].

What this lever does

Lever 2 increases the outward K⁺ (M-current) brake, hyperpolarising the neuron and restoring its OFF basin. The K_V7 family is the template (a clinically realised opener arm). The promoter reads place each gene on the threshold scale; direction is cited Layer-2 biology, reads are [V], clinical magnitudes are [O].

Targets in this lever

Each row links to that target's own self-contained page (its read, grades, citation, and firewall).